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RESEARCH

 

Research Highlights

New Real Time Technology for Brain Diseases Monitors Effects of Medicine

  • June 23, 2015
  • Hit 3959
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Professor Kim Jeong Hun
Professor Kim Jeong Hun

Professor KIM Jeong Hun (Department of Ophthalmology, College of Medicine) and LEE Tae Geol (Center for Nano-Bio Measurement, Korea Research Institute of Standards and Science Daejeon) have measured the capacitance (the ability of a body to store an electrical charge) of endothelial cells that construct blood vessels and monitored the decreasing effect of vascular permeability when medicine is injected in real time.

Until now, to see how a medicine affected cells or proteins it was necessary for the target protein that constructs a cell to be marked with fluorescent materials and observed by fluorescence microscopes. Moreover, it usually took about 2 or 3 days after injection to see the effects of medicine and was hard to analyze quantitatively due to the inaccuracy of human eyes through microscopes.

With this new technology, however, by incubating multiple cells of the same type simultaneously and monitoring electrical charges of cells in real time, it is possible to increase the effectiveness of medicine and experiment with multiple medicines on a single target cell. The research team plans to increase the number of incubating facilities to accelerate determination of the best medications and dosages to administer as well.

Professor KIM and Dr. LEE said, “Now, it is possible to see how a medicine works before applying it to human beings through our technology. We expect that it will be utilized in many areas including for the treatment of brain diseases.”

List of postings
NO. TITLE DATE HIT
171 New Real Time Technology for Brain Diseases Monitors Effects of Medicine June 23, 2015 3959
170 Professor Yoon-Sik LEE Enables Direct Identification of Peptides Using SERS Barcoding System June 8, 2015 3739
169 New Treatment for Liver Cancer Lowers Death Rate by Seventy-Nine Percent May 29, 2015 4776
168 Professor LEE Byoung Ho Develops High Technology Color Filter May 26, 2015 4079
167 Professor Sung Hoon KIM Receives Hoam Award in Medicine May 22, 2015 3609