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Disease-specific eQTL screening reveals an anti-fibrotic effect of AGXT2 in non-alcoholic fatty liver disease
Prof. Won Kim
Genome-wide association studies have revealed a limited contribution of genomic variants to the disease, requiring alternative but robust approaches to identify disease-associated variants and genes.
Research Highlights Board
Synthetic protein quality control to enhance full-length translation in bacteria
Prof. Sang Woo Seo
Coupled transcription and translation processes in bacteria cause indiscriminate translation of intact and truncated messenger RNAs, inevitably generating nonfunctional polypeptides.
Vibrio cholerae FruR facilitates binding of RNA polymerase to the fru promoter in the presence of fr...
Prof. Yeong-Jae Seok
In most bacteria, efficient use of carbohydrates is primarily mediated by the phosphoenolpyruvate (PEP):carbohydrate phosphotransferase system (PTS), which concomitantly phosphorylates the substrates during import.
Reversible disorder-order transitions in atomic crystal nucleation
Prof. Jungwon Park
Nucleation in atomic crystallization remains poorly understood, despite advances in classical nucleation theory.
Highly luminescent and catalytically active suprastructures of magic-sized semiconductor nanocluster...
Prof. Taeghwan Hyeon
Metal chalcogenide magic-sized nanoclusters have shown intriguing photophysical and chemical properties, yet ambient instability has hampered their extensive applications. Here we explore the periodic assembly of these nanoscale building blocks through organic linkers to overcome such limitations and further boost thei...
FAX-RIC enables robust profiling of dynamic RNP complex formation in multicellular organisms in vivo
Prof. Jong-Seo Kim, V Narry Kim
RNA–protein interaction is central to post-transcriptional gene regulation. Identification of RNA-binding proteins relies mainly on UV-induced crosslinking (UVX) followed by the enrichment of RNA–protein conjugates and LC-MS/MS analysis.
PLEIO: a method to map and interpret pleiotropic loci with GWAS summary statistics
Prof. Buhm Han
Identifying and interpreting pleiotropic loci is essential to understanding the shared etiology among diseases and complex traits.
Single EMG Sensor-Driven Robotic Glove Control for Reliable Augmentation of Power Grasping
Prof. Jooeun Ahn
The practical operation of wearable robots requires intuitive, compact, yet reliable control interfaces.
Emotional well-being and gut microbiome profiles by enterotype
Prof. Jongsik Chun & Incheol Choi
With increasing attention being paid to improving emotional well-being, recent evidence points to gut microbiota as a key player in regulating mental and physical health via bidirectional communication between the brain and gut.
Fingerprint ridges allow primates to regulate grip
Prof. Gun-Sik Park
Here, we found that fingerprints were at the origin of a moisture-regulating mechanism.
Soft Miniaturized Actuation and Sensing Units for Dynamic Force Control of Cardiac Ablation Catheter...
Prof. Yong-Lae Park
Recently, there has been active research in finding robotized solutions for the treatment of atrial fibrillation (AF) by augmenting catheter systems through the integration of force sensors at the tip.
Permselective metal–organic framework gel membrane enables long-life cycling of rechargeable organic...
Prof. Kisuk Kang
Rechargeable organic batteries show great potential as a low-cost, sustainable and mass-producible alternatives to current transition-metal-based cells