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Disease-specific eQTL screening reveals an anti-fibrotic effect of AGXT2 in non-alcoholic fatty liver disease
Prof. Won Kim
Genome-wide association studies have revealed a limited contribution of genomic variants to the disease, requiring alternative but robust approaches to identify disease-associated variants and genes.
Research Highlights Board
Identification of water-infiltration-induced electrical energy generation by ionovoltaic effect in p...
Prof. Youn Sang Kim
We verified the origin of water-infiltration-induced electricity generation by an ionovoltaic effect, specifically, ion–surface interaction induced potential asymmetry in porous structures. When 20 μl of water (NaCl, 0.1 M) infiltrates into a porous CuO nanowire film, electrical power of ∼0.45 V and ∼0.23 μA is produce...
A system-level approach identifies HIF-2α as a critical regulator of chondrosarcoma progression
Prof. Jin-Hong Kim
Chondrosarcomas, malignant cartilaginous neoplasms, are capable of transitioning to highly aggressive, metastatic, and treatment-refractory states, resulting in significant patient mortality.
The mosaic genome of indigenous African cattle as a unique genetic resource for African pastoralism
Prof. Heebal Kim
Cattle pastoralism plays a central role in human livelihood in Africa. However, the genetic history of its success remains unknown.
Multioperation‐Mode Light‐Emitting Field‐Effect Transistors Based on van der Waals Heterostructure
Prof. Gwan‐Hyoung Lee
2D semiconductors have shown great potential for application to electrically tunable optoelectronics.
DNA Micro‐Disks for the Management of DNA‐Based Data Storage with Index and Write‐Once–Read‐Many (WO...
Prof. Sunghoon Kwon
DNA‐based data storage has attracted attention because of its higher physical density of the data and longer retention time than those of conventional digital data storage. However, previous DNA‐based data storage lacked index features and the data quality of storage after a single access was not preserved, obstructing...
Novel laser-thermal mechanism realizes ultra-fast construction of PDMS devices
Prof. Seung Hwan Ko
Researchers at Seoul National University in South Korea reported the development of new laser-based polydimethylsiloxane (PDMS) processing mechanism that enables the mask-less direct fabrication of various PDMS structures.
Rhizolutin, a novel 7/10/6‐tricyclic dilactone, dissociates misfolded protein aggregates and reduces...
Prof. Dong-Chan Oh
Rhizolutin ( 1 ) was discovered as a natural product of ginseng‐rhizospheric Streptomyces sp. WON17. Its structure featured an unprecedented 7/10/6‐tricyclic dilactone carbon skeleton composed of dimethylcyclodecatriene flanked by a 7‐membered and a 6‐membered lactone ring based on spectroscopic analysis. During an unb...
A Large‐Scale Array of Ordered Graphene‐Sandwiched Chambers for Quantitative Liquid‐Phase Transmissi...
Prof. Jungwon Park
Liquid‐phase transmission electron microscopy (TEM) offers a real‐time microscopic observation of the nanometer scale for understanding the underlying mechanisms of the growth, etching, and interactions of colloidal nanoparticles. Despite such unique capability and potential application in diverse fields of analytical ...
Monolithic digital patterning of polydimethylsiloxane with successive laser pyrolysis
Prof. Seung Hwan Ko & Prof. Noo Li Jeon
The patterning of polydimethylsiloxane (PDMS) into complex two-dimensional (2D) or 3D shapes is a crucial step for diverse applications based on soft lithography. Nevertheless, mould replication that incorporates time-consuming and costly photolithography processes still remains the dominant technology in the field. He...
Quantum distance and anomalous Landau levels of flat bands
Prof. Bohm-Jung Yang
Semiclassical quantization of electronic states under a magnetic field, as proposed by Onsager, describes not only the Landau level spectrum but also the geometric responses of metals under a magnetic field. Even in graphene with relativistic energy dispersion, Onsager’s rule correctly describes the π Berry phase, as w...
Urolithin A suppresses high glucose-induced neuronal amyloidogenesis by modulating TGM2-dependent ER...
Prof. Ho Jae Han
Hyperglycemia in diabetes mellitus (DM) patients is a causative factor for amyloidogenesis and induces neuropathological changes, such as impaired neuronal integrity, neurodegeneration, and cognitive impairment.
Resource-Efficient Topological Fault-Tolerant Quantum Computation with Hybrid Entanglement of Light
Prof. Hyunseok Jeong
We propose an all-linear-optical scheme to ballistically generate a cluster state for measurement-based topological fault-tolerant quantum computation using hybrid photonic qubits entangled in a continuous-discrete domain.